But if you want to take your time as you gawk your way through scenic viewpoints, i recommend taking a few days to squeeze in all the quirky and beautiful roadside attractions this route has to offer. You can also compare the travel time if you're flying or driving by calculating the distance from miami to key west. Miami To Key West Drive 25 Amazing Stops In 2021 Travel Key West Florida Travel Guide Key West Vacations Miami to key west road trip faqs q: Drive to miami to key west . Miami to key west drive background info. From miami to key west it’s all of 160 miles via the overseas highway. And, there are quite a few cool places to see. One of the biggest mistakes people make when embarking on the drive from miami to key west is that they don’t stop except for food and gas. Ad find & book the best things to do, tours, activities, excursions & more. Try searching for places within 3.5 hours of key west. This part of the us feels like it’s. How long is...